根据名称进行药物检索

Nifedical XL与食物

Nifedical XL与食物安全配伍检测的结果。

检测结果:

Nifedical XL <> 食物

现实性: 03.07.2019 评论家: 医学副博士Shkutko P.M., in

通过权威的信息来源 Drugs.com、Rxlist.com、Webmd.com、Medscape.com，在进行所选药物与这种食物或生活方式互相作用检测时，发现一些会产生负面影响或对身体危害的禁忌症及副作用。

用户:

你应该避免或限制消费的柚子和柚子汁如果你正在接受治疗与硝苯地平。柚子汁可以显着增加，血液水平和效果的药物，如硝苯地平。你可能会更有可能经历的副作用，例如头痛低血压、心律不齐、肿胀和流体保留。谈谈你的医生或药剂师，如果你有任何疑问或关切的问题。重要的是要告诉你的医生关于所有其他药物的使用，包括维生素和草药。不停止使用任何药物，没有第一个说你的医生。

医界专家:

一般避免的消耗柚子汁可能与显着增加等离子体浓度的一些钙通道阻滞剂(建行)时，他们是口服给药。拟议的机制是抑制CYP450 3A4介导的第一次通过新陈代谢的肠道墙的某些化合物的存在柚子。相互作用已经报告了与氢吡啶建行(在大约减少的数量级)洛地平、尼索、硝苯地平、和尼莫地平，往往有高度的个体差的可变性。柚子汁造成超过两个方面增加了在洛地平、硝苯地平、和尼索AUCs.

管理：制造商的硝苯地平和尼索建议避免柚子汁。治疗的病人口与其他钙通道阻滞剂应当建议避免食用大量的葡萄柚和柚子汁以防止任何不适当的波动，在血清的药物水平。增加血压的影响可能会持续到4天之后消费的柚子汁。监测钙通道阻止程序的不利影响(例如头痛低血压、晕厥、心动过速、水肿)建议。

来源

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